Aegle Alliance

Suture Material

What is Poliglecaprone 25?

DemeCAPRONE (Poliglecaprone 25) is a synthetic monofilament absorbable suture composed of Poly (glycolic-co-caprolactone) copolymer (PGCL). It is supplied in violet and colorless, available in sizes 2 through 6/0.

DemeCAPRONE elicits a minimal acute inflammatory reaction in tissues, followed by gradual encapsulation by fibrous connective tissue. Absorption occurs by hydrolysis and is essentially complete in approximately 90 to 120 days.

DemeTech's fast absorbing Poliglecaprone 25 offers very high initial tensile strength, excellent handling properties and high pliability — making it well suited to a broad range of surgical applications.

More Details

PGCLGlycolide & ε-Caprolactone Copolymer

90–120Days — Complete Absorption

MonoFilament Construction

Violet / ColorlessAvailable Colours

How It Works

Actions in Tissue

Understanding how Poliglecaprone 25 behaves once placed in the body

DemeCAPRONE (Poliglecaprone 25) synthetic absorbable sutures elicit a minimal acute inflammatory reaction in tissues, characteristic of a foreign body response. This is followed by gradual encapsulation of the suture by fibrous connective tissue.

Progressive loss of tensile strength and eventual absorption occurs by means of hydrolysis. Absorption begins as a loss of tensile strength followed by a loss of mass, and is essentially complete in approximately 90 to 120 days.

Minimal Tissue Reaction

DemeCAPRONE elicits a minimal acute inflammatory reaction in tissues, characteristic of a foreign body response, followed by gradual encapsulation by fibrous connective tissue.

Absorption by Hydrolysis

Progressive loss of tensile strength and eventual absorption occur by hydrolysis. Absorption begins as a loss of tensile strength, followed by loss of mass — a clean, predictable process.

Complete Absorption Timeline

Absorption is essentially complete in approximately 90 to 120 days. DemeCAPRONE is available in sizes 2 through 6/0 to cover a broad spectrum of surgical needs.

DemeTech's fast absorbing Poliglecaprone 25 is made of a synthetic absorbable monofilament composed of glycolide and ε-caprolactone copolymer (PGCL). Available in violet or colorless, DemeCAPRONE delivers very high initial tensile strength alongside excellent handling properties and high pliability — with a very low incidence of infection and trauma, smooth tissue passage, reliable absorption, and high in vivo strength retention.

Very High Initial Tensile Strength

DemeCAPRONE provides very high tensile strength immediately post-implantation, giving surgeons confident wound closure from the moment the suture is placed.

Excellent Handling & High Pliability

Exceptional handling properties and high pliability make DemeCAPRONE easy to work with, supporting precise suturing technique across a wide range of procedures.

Very Low Infection & Trauma Risk

The monofilament construction and PGCL copolymer result in a very low incidence of infection and tissue trauma, reducing postoperative complications.

Smooth Tissue Passage

Passes smoothly through tissue with minimal drag, reducing mechanical trauma at the suture line and contributing to a cleaner surgical field.

Reliable Absorption

Consistent hydrolysis-based absorption with a well-defined 90–120 day timeline ensures predictable degradation without residual foreign body material.

High In Vivo Strength Retention

Maintains high in vivo strength retention through the critical wound healing period, providing sustained structural support where it matters most.

Usage

Indications

Do not re-sterilize. Contents are sterile unless packaging has been opened or damaged. Discard open, unused sutures. Store at room temperature. Avoid prolonged exposure to elevated temperatures.
As with any foreign body, prolonged contact with salt solutions such as those found in the urinary or biliary tracts may result in calculus formation.
Users should be familiar with surgical procedures and techniques involving absorbable sutures before employing DemeCAPRONE for wound closure, as the risk of wound dehiscence may vary with the site of application and the suture material used.
Acceptable surgical procedure must be followed with respect to drainage and closure of contaminated or infected wounds.
The use of this suture may be inappropriate for patients with any conditions which may cause or contribute to delayed wound healing. The use of supplemental non-absorbable sutures should be considered for sites subject to expansion, stretching, or distention, or requiring additional support.
Users should exercise caution when handling surgical needles to avoid inadvertent needle stick injury. Discard used needles in 'Sharps' containers.
Do not reuse. The reuse of single-use devices can cause cross contamination and affect device safety, performance, and effectiveness, exposing patients and staff to unnecessary risk.

Safety

Precautions

Under some circumstances, notably orthopedic procedures, immobilization by external support may be employed at the discretion of the surgeon.
Skin sutures which must remain in place longer than 7 days may cause localized irritation and should be snipped off or removed as indicated. Subcuticular sutures should be placed as deeply as possible to minimize erythema and induration.
Care should be taken to avoid damage from handling. Avoid crushing or crimping damage due to application of surgical instruments such as forceps or needle holders.
DemeCAPRONE suture knots must be properly placed to be secure. Adequate knot security requires flat and square ties with additional throws as warranted by surgical circumstance. Additional throws may be particularly appropriate when knotting monofilaments.
To avoid damaging needle points and swage areas, grasp the needle one-third to one-half of the distance from the swaged end to the point. Reshaping needles may reduce strength and bending resistance. Discard used needles in "sharps" containers.
Consideration should be taken in the use of absorbable sutures in tissue with poor blood supply as suture extrusion and delayed absorption may occur. Avoid prolonged exposure to elevated temperature.
Broken needles may result in extended or additional surgeries or residual foreign bodies, and inadvertent needle sticks involving contaminated surgical needles can result in transmission of bloodborne pathogens.

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